Any blockage in the oil pickup that will cause problems will be directly seen in the oil pressure readings. Therefore, if you are reasonably sure that your engine is clean, but are still freaking out that your screen may be clogged (or clogging), just install an oil pressure gauge. I got a stepper motor gauge off ebay for like $80.
I think this is an especially good idea if you plan on doing (or have done) engine flushes like AutoRX or Seafoam or Diesel fuel or what-have-you. Those job of those products is to loosen the crap-ola in 'jo engine. However, if the chunks of crap are too big to go through the screen, they can get caught in it and make the problem worse (ie: a cleaner top end, but a more clogged screen). A simple gauge is excellent insurance. It gives me so much reassurance to look at that gauge and see plenty of nice, happy oil pressure.
The Auto-RX product supposedly uses lanolin and other ingredients to slowly soften the sludge and dilute it into the oil for capture by the filter (not the screen). It should theoretically be able to soften and rinse away the deposits that are already in the screen. Seeing first hand what clogs those screens, I think that's a long shot.
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